Ioning out glioblastoma: ferroptosis mechanisms and therapeutic frontiers
8.0
来源：
Nature
发布时间：
2025-08-26 19:40
摘要：
The article explores the mechanisms of ferroptosis as a novel therapeutic strategy for glioblastoma, emphasizing its potential to overcome treatment resistance. It discusses the unique molecular pathways involved in ferroptosis and their implications for targeted therapies, including the use of nanomedicine for enhanced drug delivery. The review highlights the need for further research to address challenges in clinical application and to develop effective combination therapies that integrate ferroptosis inducers with existing treatment modalities.
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关键证据
Ferroptosis represents a potential therapeutic target for GBM.
Innovative applications of nano-drug delivery technologies are discussed.
The article outlines future research directions for ferroptosis signaling hubs.
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AI评分总结
The article explores the mechanisms of ferroptosis as a novel therapeutic strategy for glioblastoma, emphasizing its potential to overcome treatment resistance. It discusses the unique molecular pathways involved in ferroptosis and their implications for targeted therapies, including the use of nanomedicine for enhanced drug delivery. The review highlights the need for further research to address challenges in clinical application and to develop effective combination therapies that integrate ferroptosis inducers with existing treatment modalities.