Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy
8.5
来源：
Cell
发布时间：
2025-09-02 03:33
摘要：
Zeaxanthin, a dietary carotenoid, has been identified as an immunomodulator that enhances CD8+ T cell function and anti-tumor immunity. Research indicates that oral supplementation with zeaxanthin significantly improves the efficacy of immunotherapy, particularly in the context of anti-PD1 immune checkpoint inhibitors. The findings suggest a novel role for dietary components in modulating immune responses, highlighting zeaxanthin's potential as a dietary supplement to bolster immunotherapy outcomes.
原文：
查看原文
价值分投票
评分标准
新闻价值分采用0-10分制，综合考虑新闻的真实性、重要性、时效性、影响力等多个维度。
评分越高，表示该新闻的价值越大，越值得关注。
价值维度分析
domain_focus
1.0
business_impact
0.5
scientific_rigor
1.5
timeliness_innovation
1.5
investment_perspective
2.5
market_value_relevance
1.0
team_institution_background
0.5
technical_barrier_competition
0.5
关键证据
Zeaxanthin enhances the cytotoxicity of CD8+ T cells.
Oral supplementation with ZEA augments anti-tumor immunity in vivo.
ZEA treatment improves immunotherapy efficacy.
真实性检查
否
AI评分总结
Zeaxanthin, a dietary carotenoid, has been identified as an immunomodulator that enhances CD8+ T cell function and anti-tumor immunity. Research indicates that oral supplementation with zeaxanthin significantly improves the efficacy of immunotherapy, particularly in the context of anti-PD1 immune checkpoint inhibitors. The findings suggest a novel role for dietary components in modulating immune responses, highlighting zeaxanthin's potential as a dietary supplement to bolster immunotherapy outcomes.