Enteroendocrine cells: the gatekeepers of microbiome-gut-brain communication
6.0
来源：
Nature
发布时间：
2025-09-02 03:59
摘要：
Enteroendocrine cells (EECs) play a crucial role in gut-brain communication, influencing various physiological processes and linked to diseases such as inflammatory bowel disease (IBD), metabolic disorders, and neurodegenerative diseases. This review highlights the metabolic and systemic roles of EECs, their interactions with dietary components and the microbiome, and identifies significant research gaps. The findings suggest that understanding EEC functions could lead to novel therapeutic strategies for managing metabolic diseases and improving gut health.
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关键证据
EECs are linked to various diseases including IBD, metabolic disorders, and neurodegenerative diseases.
The review identifies research gaps in EEC functions and their interactions with the microbiome.
The study discusses global implications of EECs in health and disease.
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AI评分总结
Enteroendocrine cells (EECs) play a crucial role in gut-brain communication, influencing various physiological processes and linked to diseases such as inflammatory bowel disease (IBD), metabolic disorders, and neurodegenerative diseases. This review highlights the metabolic and systemic roles of EECs, their interactions with dietary components and the microbiome, and identifies significant research gaps. The findings suggest that understanding EEC functions could lead to novel therapeutic strategies for managing metabolic diseases and improving gut health.