The reference genome of the human diploid cell line RPE-1
6.0
来源：
Nature
关键字：
computational biology
发布时间：
2025-09-12 19:44
摘要：
The article presents the RPE1v1.1 genome assembly, a near-complete diploid genome of the hTERT RPE-1 cell line, which is crucial for genetic and epigenetic research. This assembly enhances the understanding of human genomic diversity and provides a reference for studies involving this widely used cell line. The work highlights the importance of high-quality genome assemblies in advancing functional genomics and addressing biological questions related to human diversity.
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关键证据
The RPE1v1.1 assembly represents the first reference-quality genome of a laboratory cell line.
This assembly supports high-precision genetic and epigenetic studies.
The study enhances understanding of human genomic diversity and the significance of laboratory cell lines.
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AI评分总结
The article presents the RPE1v1.1 genome assembly, a near-complete diploid genome of the hTERT RPE-1 cell line, which is crucial for genetic and epigenetic research. This assembly enhances the understanding of human genomic diversity and provides a reference for studies involving this widely used cell line. The work highlights the importance of high-quality genome assemblies in advancing functional genomics and addressing biological questions related to human diversity.