Lupus nephritis
6.0
来源：
Nature
关键字：
TCR-T
发布时间：
2025-09-25 19:34
摘要：
Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), affecting a significant percentage of patients. The article discusses the complex pathogenesis of LN, including immune dysregulation and key signaling pathways. It emphasizes the importance of early diagnosis and multidisciplinary care in managing LN, highlighting advancements in treatment options and the shift towards personalized therapy. The ongoing research and updated guidelines reflect the critical need for effective management strategies to improve patient outcomes.
原文：
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domain_focus
1.0分+医疗健康重点关注领域符合度
business_impact
0.5分+商业影响力
scientific_rigor
1.5分+数据支撑的科学性
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关键证据
Lupus nephritis affects 25–60% of patients with systemic lupus erythematosus.
The pathogenesis involves complex immune dysregulation.
Several immunomodulatory drugs are used for the management of lupus nephritis.
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AI评分总结
Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), affecting a significant percentage of patients. The article discusses the complex pathogenesis of LN, including immune dysregulation and key signaling pathways. It emphasizes the importance of early diagnosis and multidisciplinary care in managing LN, highlighting advancements in treatment options and the shift towards personalized therapy. The ongoing research and updated guidelines reflect the critical need for effective management strategies to improve patient outcomes.