Meta-analysis of comprehensive prognostic evaluation in patients with atrial fibrillation complicated by heart failure after catheter ablation

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来源: Nature 关键字: ML brain science
发布时间: 2025-09-26 03:36
摘要:

This systematic review and meta-analysis assess the effectiveness of catheter ablation (CA) in patients with atrial fibrillation (AF) and heart failure (HF). The analysis includes 34 studies with a total of 777,668 patients, revealing that CA significantly reduces the risk of HF events, cardiovascular mortality, and rehospitalization compared to non-ablation therapies. The findings support the early intervention of CA in managing AF-HF patients, highlighting its potential to improve clinical outcomes and quality of life.

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关键证据

CA significantly reduced the risk of HF events (RR, 0.63; 95% CI, 0.51–0.77).
Meta-analysis systematically includes high-quality RCTs and cohort studies comprising 777,668 patients.
CA demonstrated superior benefits in improving outcomes for patients with AF and HF.

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AI评分总结

This systematic review and meta-analysis assess the effectiveness of catheter ablation (CA) in patients with atrial fibrillation (AF) and heart failure (HF). The analysis includes 34 studies with a total of 777,668 patients, revealing that CA significantly reduces the risk of HF events, cardiovascular mortality, and rehospitalization compared to non-ablation therapies. The findings support the early intervention of CA in managing AF-HF patients, highlighting its potential to improve clinical outcomes and quality of life.

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