Hydrogel dressing containing natural extracts inhibits dual-species biofilms of Staphylococcus aureus and Acinetobacter baumannii in ex vivo wound infection models
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来源：
Nature
关键字：
ML brain science
发布时间：
2025-10-03 23:40
摘要：
RQ hydrogel, developed from Rhodomyrtus tomentosa and Quercus infectoria extracts, effectively inhibits dual-species biofilms of Staphylococcus aureus and Acinetobacter baumannii in ex vivo wound infection models. It demonstrated significant antibacterial and antioxidant activities, making it a promising alternative for treating chronic wound infections. The hydrogel's formulation is biocompatible, indicating its potential for clinical applications in wound care.
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关键证据
RQ hydrogel could inhibit up to 7 log CFU/mL of pathogens.
The hydrogel showed significant antibacterial activity against both Gram-positive and Gram-negative bacteria.
The study confirmed the biocompatibility of the hydrogel with L929 fibroblast cells.
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AI评分总结
RQ hydrogel, developed from Rhodomyrtus tomentosa and Quercus infectoria extracts, effectively inhibits dual-species biofilms of Staphylococcus aureus and Acinetobacter baumannii in ex vivo wound infection models. It demonstrated significant antibacterial and antioxidant activities, making it a promising alternative for treating chronic wound infections. The hydrogel's formulation is biocompatible, indicating its potential for clinical applications in wound care.