HypoxamiRs: the hidden architects of tissue adaptation in hypoxia
7.3
来源：
Nature
关键字：
neural coding
发布时间：
2025-10-16 23:56
摘要：
HypoxamiRs are critical regulators of tissue adaptation to hypoxia, influencing processes such as angiogenesis, metabolic reprogramming, and survival pathways. They are being investigated as non-invasive biomarkers and therapeutic targets in various diseases, including cancer and cardiovascular disorders. The review emphasizes their potential in precision medicine, highlighting the need for further research to unlock their full therapeutic capabilities.
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关键证据
HypoxamiRs are increasingly recognized as non-invasive biomarkers and therapeutic targets in diseases such as cancer, cardiovascular disorders, and fibrosis.
The review presents a unified framework in which hypoxamiRs emerge not merely as downstream effectors of HIF signaling but as integrative architects.
Understanding how hypoxamiRs operate across tissues and pathologies may unlock new diagnostic and therapeutic strategies.
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AI评分总结
HypoxamiRs are critical regulators of tissue adaptation to hypoxia, influencing processes such as angiogenesis, metabolic reprogramming, and survival pathways. They are being investigated as non-invasive biomarkers and therapeutic targets in various diseases, including cancer and cardiovascular disorders. The review emphasizes their potential in precision medicine, highlighting the need for further research to unlock their full therapeutic capabilities.