Fatigue: a common but poorly understood symptom in neurological and non-neurological diseases
6.5
来源：
Nature
关键字：
digital pathology
发布时间：
2025-10-25 04:02
摘要：
Fatigue is a complex and disabling symptom prevalent in both neurological and non-neurological diseases, significantly impacting patients' quality of life. The article proposes a new taxonomy to better understand fatigue's origins and emphasizes the need for large-scale research to address its multifactorial nature. It highlights the interplay of genetics, immunological changes, and behavioral factors in fatigue, advocating for a multidisciplinary approach to management.
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关键证据
Fatigue is a major unmet medical need with serious socioeconomic implications.
The proposed taxonomy includes neurogenic, myogenic, and systemic clusters.
Understanding the complexity of fatigue is essential for improving diagnostic processes.
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AI评分总结
Fatigue is a complex and disabling symptom prevalent in both neurological and non-neurological diseases, significantly impacting patients' quality of life. The article proposes a new taxonomy to better understand fatigue's origins and emphasizes the need for large-scale research to address its multifactorial nature. It highlights the interplay of genetics, immunological changes, and behavioral factors in fatigue, advocating for a multidisciplinary approach to management.