Innovent, Lillys mazdutide trumps Novos semaglutide in head-to-head diabetes, weight loss study
6.5
来源：
FiercePharma
发布时间：
2025-10-27 11:11
摘要：
Mazdutide, developed by Innovent and Eli Lilly, has demonstrated superior efficacy compared to Novo Nordisk's semaglutide in a phase 3 trial for type 2 diabetes and obesity. The trial showed that 48% of patients on mazdutide achieved significant improvements in blood sugar and weight loss, compared to 21% on semaglutide. Approved in China, mazdutide represents a breakthrough in incretin therapies, with ongoing studies planned for various patient populations and conditions.
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关键证据
Mazdutide outperformed semaglutide in both blood sugar and weight loss metrics.
The drug is the first approved GLP-1/GCG dual receptor agonist.
Innovent and Lilly's partnership has led to significant advancements in diabetes treatment.
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AI评分总结
Mazdutide, developed by Innovent and Eli Lilly, has demonstrated superior efficacy compared to Novo Nordisk's semaglutide in a phase 3 trial for type 2 diabetes and obesity. The trial showed that 48% of patients on mazdutide achieved significant improvements in blood sugar and weight loss, compared to 21% on semaglutide. Approved in China, mazdutide represents a breakthrough in incretin therapies, with ongoing studies planned for various patient populations and conditions.