The multifaceted role of hair as a biospecimen: recent advances in precision medicine and forensic science

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来源: Nature 关键字: ML brain science
发布时间: 2025-10-27 23:34
摘要:

Hair specimens are increasingly recognized as vital in precision medicine and forensic science due to their ability to retain biochemical data over time. They offer noninvasive collection methods and long-term storage suitability, making them ideal for diagnostics. Recent advancements in analytical techniques, such as mass spectrometry and chromatography, have broadened their applications in cancer diagnostics, monitoring treatment efficacy, and assessing mental health. However, challenges like hair growth variability and contamination remain significant hurdles to their widespread use.

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关键证据

Hair analysis provides a long-term biochemical profile, aiding in monitoring health conditions, nutritional deficiencies, toxin exposure and treatment efficacy.
Advances in mass spectrometry, chromatography and spectroscopy have expanded their applications to cancer diagnostics, tuberculosis, HIV, neurological disorders and mental health assessments.
Despite its potential, challenges such as hair growth variability, contamination and lack of standardized techniques limit the current impact of hair analysis.

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AI评分总结

Hair specimens are increasingly recognized as vital in precision medicine and forensic science due to their ability to retain biochemical data over time. They offer noninvasive collection methods and long-term storage suitability, making them ideal for diagnostics. Recent advancements in analytical techniques, such as mass spectrometry and chromatography, have broadened their applications in cancer diagnostics, monitoring treatment efficacy, and assessing mental health. However, challenges like hair growth variability and contamination remain significant hurdles to their widespread use.

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