Olfactory gene dynamics in invasive Indian and non-invasive African malaria vectors at the crossroads of development, infection and resistance
5.5
来源：
Nature
关键字：
computational biology
发布时间：
2025-10-29 03:52
摘要：
This study provides a comprehensive catalog of olfactory genes in invasive Indian (A. stephensi) and non-invasive African malaria vectors (A. gambiae, A. funestus). It reveals significant differences in gene counts and expression patterns, particularly highlighting the role of odorant-binding proteins (OBPs) in insecticide resistance. The findings underscore the potential threat posed by A. stephensi's invasion into Africa, emphasizing the need for innovative malaria control strategies that consider the genetic and ecological dynamics of these vectors.
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关键证据
The study catalogs olfactory genes for key malaria vectors.
Significantly higher number of olfactory genes in African malaria vectors.
Findings suggest potential roles of OBPs in insecticide resistance.
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AI评分总结
This study provides a comprehensive catalog of olfactory genes in invasive Indian (A. stephensi) and non-invasive African malaria vectors (A. gambiae, A. funestus). It reveals significant differences in gene counts and expression patterns, particularly highlighting the role of odorant-binding proteins (OBPs) in insecticide resistance. The findings underscore the potential threat posed by A. stephensi's invasion into Africa, emphasizing the need for innovative malaria control strategies that consider the genetic and ecological dynamics of these vectors.