Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents—a systematic review with meta-analysis of animal trials
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来源：
Nature
关键字：
AI brain science
发布时间：
2025-10-30 23:34
摘要：
Collagen peptides have demonstrated significant anti-obesity effects in rodent models, according to a systematic review and meta-analysis. The findings indicate reductions in body mass, food intake, and improvements in glucose metabolism and lipid profiles. Despite the promising results, the certainty of evidence remains low, highlighting the need for further research in human trials to validate these effects and explore the underlying mechanisms.
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关键证据
Collagen peptide supplementation led to significant decreases in body mass and food intake.
The systematic review included 21 studies with a total of 339 rodents.
Collagen peptides showed potential to improve glucose metabolism and lipid profiles.
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AI评分总结
Collagen peptides have demonstrated significant anti-obesity effects in rodent models, according to a systematic review and meta-analysis. The findings indicate reductions in body mass, food intake, and improvements in glucose metabolism and lipid profiles. Despite the promising results, the certainty of evidence remains low, highlighting the need for further research in human trials to validate these effects and explore the underlying mechanisms.