Four-class classification of tumor-induced colorectal obstruction histopathology: A ResNet–mamba-mased study on cellular interaction pattern recognition

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来源: Nature 关键字: computational pathology
发布时间: 2025-11-13 07:43
摘要:

This study introduces a deep learning model for the classification of tumor-induced colorectal obstruction (TICO) lesions, achieving an 85% validation accuracy. Utilizing a ResNet-Mamba architecture, the model analyzes cellular interaction patterns in histopathological slides, demonstrating strong diagnostic potential. The research focuses on four histological categories: normal mucosa, serrated lesions, adenomas, and adenocarcinomas, providing a foundation for early diagnosis and personalized treatment strategies in oncology.

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关键证据

The model achieved a validation accuracy of 85% and a macro-F1 score of 0.843.
The proposed deep learning framework combines a residual convolutional network with a bidirectional state-space module.
The study highlights the model's potential for early diagnosis and personalized treatment strategies.

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This study introduces a deep learning model for the classification of tumor-induced colorectal obstruction (TICO) lesions, achieving an 85% validation accuracy. Utilizing a ResNet-Mamba architecture, the model analyzes cellular interaction patterns in histopathological slides, demonstrating strong diagnostic potential. The research focuses on four histological categories: normal mucosa, serrated lesions, adenomas, and adenocarcinomas, providing a foundation for early diagnosis and personalized treatment strategies in oncology.

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