Chemical finger-printing, antioxidant activity and in silico validation of phytometabolites of Octhochloa compressa
6.5
来源：
Nature
关键字：
computational biology
发布时间：
2025-11-21 23:53
摘要：
This study investigates the antioxidant properties of Octhochloa compressa, a medicinal plant from Pakistan. It evaluates various solvent extracts for their antioxidant activity using DPPH and FRAP assays, identifying key bioactive compounds through HPLC and GC-MS. Molecular docking studies with NADPH oxidase suggest potential therapeutic applications in managing oxidative stress-related disorders. The findings underscore the plant's rich source of antioxidants and its relevance in traditional medicine.
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关键证据
The methanol extract revealed significantly highest scavenging potential (IC50 = 110 ± 2.34 µg/mL) in DPPH assay.
Molecular docking of selected metabolites with NADPH oxidase revealed stable interactions.
The study systematically evaluated the antioxidant potential of six different extracts.
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AI评分总结
This study investigates the antioxidant properties of Octhochloa compressa, a medicinal plant from Pakistan. It evaluates various solvent extracts for their antioxidant activity using DPPH and FRAP assays, identifying key bioactive compounds through HPLC and GC-MS. Molecular docking studies with NADPH oxidase suggest potential therapeutic applications in managing oxidative stress-related disorders. The findings underscore the plant's rich source of antioxidants and its relevance in traditional medicine.