CD3L1 expression and its association with the tumor microenvironment in 62 cases of osteosarcoma and Chordoma
7.0
来源：
Nature
关键字：
mRNA
发布时间：
2025-11-27 03:56
摘要：
CD3L1 expression was evaluated in 62 cases of osteosarcoma and chordoma, revealing its significant association with immune cell infiltration, particularly in chordoma. The findings suggest that CD3L1 may play a crucial role in tumor-immune interactions and could serve as a potential therapeutic target. This research highlights the need for further investigation into CD3L1's clinical relevance and its implications for treatment strategies in these malignancies.
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1.0
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1.5
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2.5
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关键证据
CD3L1 was detected in 62.9% of cases, with significant associations with immune cell infiltration.
The study provides the first comprehensive assessment of CD3L1 protein expression in osteosarcoma and chordoma.
CD3L1 may serve as a novel biomarker or therapeutic target in these malignancies.
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AI评分总结
CD3L1 expression was evaluated in 62 cases of osteosarcoma and chordoma, revealing its significant association with immune cell infiltration, particularly in chordoma. The findings suggest that CD3L1 may play a crucial role in tumor-immune interactions and could serve as a potential therapeutic target. This research highlights the need for further investigation into CD3L1's clinical relevance and its implications for treatment strategies in these malignancies.