Multimodal single cell analyses reveal gene networks of planarian stem cell differentiation
7.4
来源：
Nature
关键字：
computational pathology
发布时间：
2025-11-28 03:44
摘要：
This study employs multimodal single-cell analyses to uncover the gene networks governing stem cell differentiation in planarians. By integrating single-cell transcriptomics with chromatin accessibility data, the research identifies key transcription factors and regulatory modules that dictate cell fate decisions. The findings not only enhance our understanding of stem cell biology but also position planarians as a valuable model for regenerative medicine research.
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关键证据
The study integrates single-cell transcriptomics and chromatin accessibility data to reveal gene networks involved in planarian stem cell differentiation.
The research highlights the use of planarians as a model organism for understanding stem cell differentiation and regeneration.
The findings underscore the regulatory logic of planarian stem cell differentiation, showcasing a comprehensive catalogue of gene regulatory networks.
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AI评分总结
This study employs multimodal single-cell analyses to uncover the gene networks governing stem cell differentiation in planarians. By integrating single-cell transcriptomics with chromatin accessibility data, the research identifies key transcription factors and regulatory modules that dictate cell fate decisions. The findings not only enhance our understanding of stem cell biology but also position planarians as a valuable model for regenerative medicine research.