A human gut metagenome-assembled genome catalogue spanning 41 countries supports genome-scale metabolic models
6.4
来源：
Nature
关键字：
ML brain science
发布时间：
2025-12-04 23:34
摘要：
HRGM2 is an enhanced Human Reference Gut Microbiome resource that includes 155,211 near-complete genomes from 4,824 prokaryotic species across 41 countries. This catalogue significantly increases the diversity and completeness of genomic data, enabling improved metabolic modeling and insights into microbial interactions associated with diseases. The resource aims to advance research in microbiome medicine and personalized health.
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关键证据
HRGM2 comprises 155,211 non-redundant near-complete genomes from 4,824 prokaryotic species across 41 countries.
This resource will facilitate reliable functional insights into gut microbiomes.
The exclusive use of these genomes improved metabolic capacity assessment.
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AI评分总结
HRGM2 is an enhanced Human Reference Gut Microbiome resource that includes 155,211 near-complete genomes from 4,824 prokaryotic species across 41 countries. This catalogue significantly increases the diversity and completeness of genomic data, enabling improved metabolic modeling and insights into microbial interactions associated with diseases. The resource aims to advance research in microbiome medicine and personalized health.