CD9, a tetraspanin in cancer: biology and therapeutic promise in acute leukemia
8.5
来源：
Nature
关键字：
mRNA
发布时间：
2025-12-05 19:33
摘要：
CD9, a tetraspanin, plays a critical role in cancer biology, particularly in acute leukemia. It serves as a reliable biomarker for diagnosis and minimal residual disease monitoring, with its expression linked to treatment outcomes. The review highlights the dual nature of CD9 as both a potential therapeutic target and a prognostic marker, emphasizing the need for further research to clarify its role in leukemia progression and treatment resistance.
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domain_focus
1.0分+1.0
business_impact
0.8分+0.8
scientific_rigor
1.5分+1.5
timeliness_innovation
1.5分+1.5
investment_perspective
2.5分+2.5
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1.0分+1.0
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0.5分+0.5
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1.0分+1.0
关键证据
CD9 is a reliable biomarker of leukemic cells and can be used for diagnosis and MRD monitoring.
The review discusses emerging therapeutic strategies that aim to target CD9 in cancer.
CD9 expression is associated with enhanced dissemination in certain cancers, influencing treatment outcomes.
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AI评分总结
CD9, a tetraspanin, plays a critical role in cancer biology, particularly in acute leukemia. It serves as a reliable biomarker for diagnosis and minimal residual disease monitoring, with its expression linked to treatment outcomes. The review highlights the dual nature of CD9 as both a potential therapeutic target and a prognostic marker, emphasizing the need for further research to clarify its role in leukemia progression and treatment resistance.