Vitisin A inhibits liver fibrosis by promoting Nrf2/HO-1 pathway and inhibiting Cuproptosis
8.0
来源：
Nature
关键字：
siRNA
发布时间：
2025-12-20 03:41
摘要：
Vitisin A has been identified as a potential therapeutic agent for liver fibrosis, demonstrating significant antifibrotic effects through the modulation of the Nrf2/HO-1 signaling pathway and inhibition of cuproptosis. The study provides compelling evidence of its efficacy in both in vitro and in vivo models, suggesting a novel approach to treating chronic liver diseases. This research highlights the importance of natural compounds in developing innovative therapies for liver conditions.
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1.5
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关键证据
Vitisin A inhibits liver fibrosis in a concentration-dependent and time-dependent manner.
The study suggests that Vitisin A is a promising therapeutic drug for the treatment of liver fibrosis.
Nrf2/HO-1 signaling is the key molecular pathway through which Vitisin A inhibits liver fibrosis.
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AI评分总结
Vitisin A has been identified as a potential therapeutic agent for liver fibrosis, demonstrating significant antifibrotic effects through the modulation of the Nrf2/HO-1 signaling pathway and inhibition of cuproptosis. The study provides compelling evidence of its efficacy in both in vitro and in vivo models, suggesting a novel approach to treating chronic liver diseases. This research highlights the importance of natural compounds in developing innovative therapies for liver conditions.